This single stamp design honored the first flight of the SPACEHAB laboratory module aboard the space shuttle Endeavour.

Shuttle mission STS-57, launched June 21, 1993, was commemorated. On STS-57, NASA leased a privately developed mid-deck augmentation module known as SPACEHAB. The module's primary objective was to support the commercial development of the space program by providing additional access to crew-tended, mid-deck locker or experiment rack space. This access is necessary to test, demonstrate, or evaluate techniques or processes in microgravity. NASA's secondary objective was to foster the development of a space infrastructure which could be marketed by private firms.

In this instance, SPACEHAB, Inc., had the capability of leasing SPACEHAB facility space to other commercial customers on subsequent flights of the module. The experiments flying inside the first SPACEHAB included investigations involving drug improvement, feeding plants, cell splitting, the first soldering experiment in space by American astronauts, and the high-temperature melting of metals. Another highlight of STS-57 was the rendezvous with the European Space Agency's European Carrier (EURECA) satellite.

The space shuttle's robot arm was used to grapple the satellite, which was lowered into Endeavour's cargo bay and stowed so it could be returned to Earth. The EURECA satellite had been on-orbit, collecting data since its deployment during Shuttle Mission STS-46 in July 1992.